Top 9 Best Rat Poison in 2022 Reviewed

If you have a rat problem, you need to eliminate it before the infestation escalates. 

  • The best way to get rid of these rodents is with high-quality rat or squirrel poison

Let’s take a look at the best rat poison on the market so that you can make a smart purchase today. Check top rat poisons. 

1. Our #1 Pick: Tomcat Bromethalin Rat & 12-mice for 1 oz Rodent Bait

Tomcat With Bromethalin Bait Chunx Pail
  • For use in and around agricultural buildings and homes
  • Norway rats, roof rats and house mice cease feeding after consuming a toxic dose
  • Kills up to 12 mice per 1 oz. block
  • Kills up to 10 rats per 4 oz. block
  • Ready to use

While the name of this product is a bit of a mouthful, it’s super straightforward to use and works amazingly well as one of the best rat poison out there.  

  • This is a pesticide that kills rodents by preventing blood clotting.

It is probably the most powerful of the products mentioned and is toxic to all animals and even people. It is best to use this with a bait station. 

It has an appealing smell for rodents which means they are going to be attracted to it almost as soon as it is put down, saving you the hassle of trying to entice them in other ways. 

It can be used indoors or outdoors and it is also suitable for all different weather conditions. 


  • It is good value for money especially when you consider the amount that you get in a tub.
  • Comes in chunk form, making it really easy to place wherever you need it.


  • Mice and rats will likely need to ingest it more than once for it to kill them.

2. #2 Pick: Just-One-Bite II Mouse & Rat bar 8pk 4-5 days Death Delay

Just One Bite II Rat & Mouse Bar 8pk 8lb
  • Norway rats, roof rats and house mice may consume a lethal dose in a single night's feeding
  • Death is delayed 4 to 5 days, so there's no bait shyness
  • Kills warfarin resistant Norway rats
  • 8 Individually wrapped 1 pound bars
  • For Use In and Around Agricultural Buildings Only

3. #3 Pick: Neogen Rodenticide Ramik Green rodenticides

Neogen Ramik Green Fish Flavored Weather Resistant Rodenticide Nuggets, 4 lb bag
  • One Of A Kind: Ramik Green Rodenticide is made of 1st Generation Anticoagulant: Diphacinone (.005%)
  • Target Rodents: Kills Rats, Mice, and Meadow Voles*
  • Effective Results: Death may occur within 4-5 days after lethal dose is consumed
  • Proven Formula: Ramik Green rodenticides are formulated with a food quality fish flavored grain mix
  • Protect Your Home: Can be used indoors and outdoors and is especially suited for wet or damp areas

This product comes in the form of pellets which can be used in a bait station to kill rats/mice.

  • This is a more humane method of rat poison although it can take a while longer to kick in. 
  • It works in both wet and dry weather conditions which are perfect no matter what your situation might be.

There is no secret that rats love to gnaw and the way this poison is set up requires them to do just that, which allows the poison to work effectively as quickly as possible. 

  • There are many pellets in one container and there is more than enough to kill an entire population of rodents.


  • Neogen Rodenticide is ideal for treating larger infestations that have spread over an entire house.
  • It has a very effective formula of ingredients and once ingested, will kill the rats right away.


  • The pellets are not safe for other animals and you should be careful where you put the bait because they can attract birds and squirrels.

4. JT Eaton Bait Block Rodenticide

JT Eaton 166004 709-PN Bait Block Rodenticide Anticoagulant Bait, Peanut Butter Flavor, for Mice and...
  • Anticoagulant block bait with specially formulated peanut butter flavor that attracts and eliminates mice and rats

This is a high-quality rat poison that is known to entire rodents to eat as quickly as possible due to its enticing peanut butter flavor.

One container of this product contains 144 chunks which could last you for some time. 

JT Eaton is known to be a great brand and this particular product is one of the best rat poisons with home/business owners around the world.

Although this rat poison works really quickly, rats will take between 1-3 days to die after ingesting it. 

  • It is peanut butter flavored which is irresistible to all rodents so is sure to work quickly.
  • It has a one-year warranty, allowing you to get your money back if you are not satisfied with the product.


  • As the name would suggest, it works on all rodents and not just rats.
  • The chunks are easy to use wherever you need to. They also have handy holes so you can hang them up easily if your rodent hotspots are in harder-to-reach places.


  • While the active ingredient in this is powerful, some rodents are known to have a resistance to it.

5. Ecoclear Products RatX Rodenticide & Rat Pellets

EcoClear Products 620101, RatX All-Natural Non-Toxic Humane Rat and Mouse Rodenticide Pellets, 1 lb....
  • Humanely eliminates rats and mice; non-toxic and safe for use around people, pets and wildlife
  • Natural method to eradicate rats and mice in just one feeding
  • RatX works from the inside out to exterminate rats, then dries them out after death to reduce odor by as much as 90%.
  • Patented mechanical kill system requires no conventional poisons
  • Formulated for Indoor & Outdoor Use. Perfect for both professional & DIY use

This is a really interesting type of rat poison that works really well but differently from other products on the market.

It blocks neural transmissions in rats, which means that they will then die of dehydration in a couple of days.

There are multiple different packet types with this, you can get the poison by itself or with baiting stations.

This is a product that is safe to use, which is why many people who have small children or pets will opt to use this. 


  • The rodents will be killed after one feeding which means there is more of the product to go around.
  • It is environmentally friendly, biodegradable, and safe for children.
  • It only works on rats so there is no chance of harming other animals or pets with the product.


  • There is no flavor to Eco-clear RatX that might entice rodents to eat it.
  • While this has earned its place on the list of best rat poison, it is a little more expensive than similar products on the market.

Related: Repellents for Squirrels

6. Contrac Blox with food-grade ingredients

18 LB Contrac Blox Rodent Control Rodenticide Kills Mice & Rats
  • CONTRAC BLOX is specially formulated with an optimal blend of food-grade ingredients and a small amount of paraffin Highly palatable, yet weatherable, CONTRAC works well in wet and dry conditions....
  • Application: Recommend changing bait out every 40-60 days if n
  • Pet safe: Contrac is LESS toxic to non-target animals in both primary and secondary poisoning situations than other single-feeding baits. The antidote, Vitamin K1, is readily available. Always use a...

This is a very palatable poison for rats because of its low wax content and the perfect blend of ingredients to entice them. 

Contract Blox is known to be a very effective product and is popular with people all over the world for killing rats.

Only one feed is needed to kill the rodents but it might take a couple of hours to kick in.

Contrac Blox has to be put in a bait station before it is set up to exterminate the rats. 


  • There is enough bait in one container to kill hundreds of rats and mice.
  • Can be used in both dry and wet weather conditions and targets rodents effectively.
  • While some rodents will have a tolerance to certain poisons, this one is known to have a very high “acceptance rate”.


  • In addition to rodents being highly attracted to Contrac Blox, dogs are also! You need to make sure this best rat poison is in a bait station that no dogs can get access to, although it is not known to be fatal to pets in general.


Now that you know some of the best rat poisons available, you can get a great product that really works in killing rats, and quickly.

  • Make a purchase today and it will be bye-bye to the rats and other rodents before you know it. 

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